pco.edge 4.2 bi USB sCMOS Camera
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pco.edge 4.2 bi USB sCMOS Camera

Step into a new realm of imaging with the pco.edge 4.2 bi sCMOS camera! This powerhouse combines cutting-edge back-illuminated technology with extraordinary quantum efficiency—up to 95%! Tailored for high-quality performance, it captures every detail with a stunning 2048 x 2048 pixel resolution.

pco.edge 4.2 bi USB sCMOS Camera

The pco.edge 4.2 bi is compact, but it doesn’t compromise on quality. Each 6.5 μm pixel is engineered for excellence. Thanks to its versatile cooling system, you can chill the sensor down to an impressive -25 °C—dramatically reducing dark current to just 0.2 e-/pixel/s. Whether your focus is UV or VIS wavelengths, this camera adapts effortlessly, making it the perfect tool for your advanced imaging needs! Dive into precision and reliability like never before.

The pco.edge 4.2 bi scientific camera provides excellent quantum efficiency combined with a high frame rate at 4.2 Megapixel resolution. This camera features a powerful USB 3.1 interface to continuously stream image data with full 16-bit dynamic range. Furthermore, the pco.edge 4.2 bi sCMOS camera includes sealed electronics to prevent dirt or dust from entering the camera.

Also, try our MachVis Lens Selector tool to help identify the perfect lens solution and PCO camera for your imaging and machine vision requirements.


Specifications :
Interface USB 3.1 Gen 1
Sensor technology back-illuminated sCMOS
Color type monochrome
Resolution 2048 x 2048 pixels
Sensor diagonal 18.8 mm
Pixel size 6.5 x 6.5 Î¼m
Maximum frame rate
@ full resolution
40 fps
Maximum pixel rate 184 MPixel/s
Peak QE 95 % @ 580 nm
Typical read noise *(1) 1.0 e-
Dark current @ sensor temperature < 0.2 @ -25 °C (e-/pixel/s)
Maximum dynamic range 26,667 : 1
Shutter type Rolling Shutter, Global Reset
Sensor cooling *(2) air & water
Additional options lightsheet scanning mode *(3),
low light mode
Dimensions (H x W x L) 85 x 80 x 109 mm
  1. *The readout noise values are given as median (med). All values are raw data without any filtering.
  2. *air = air forced with fan | water = external water connection
  3. *Selectable via software


Applications :
  • Brightfield microscopy microscopy
  • Fluorescence microscopy
  • Digital pathology
  • Single molecule localization microscopy
  • Lightsheet fluorescence microscopy (LSFM)
  • Calcium imaging
  • FRET
  • FRAP
  • Structured illumination microscopy (SIM)
  • Highspeed bright field ratio imaging
  • High throughput screening
  • High content screening
  • Biochip reading
  • TIRF microscopy
  • Spinning disk confocal microscopy
  • 3D metrology
  • Ophthalmology
  • Photovoltaic inspection
  • Industrial quality inspection
  • Lucky astronomy
  • Bio luminescence
  • Chemo luminescence


Brochure & Datasheet :

   pco.edge 4.2 bi USB Datasheet (pdf / English)

   pco.edge 4.2 bi and bi UV User Manual (pdf / English)

   pco.aquamatic III User Manual (pdf / English)

   pco.edge 4.2 bi 2D & 3D Mechanical Drawing (zip / pdf / English)


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